HETEROCYCLIC SYNTHESIS WITH ACTIVATED NITRILES: AND EXPEDITUS SYNTHETIC APPROACH TO POLYFUNCTIONALLY SUBSTITUTED HETEROCYCLO PYRIMIDINES, PYRAZOLO, CHROMENO AND TETRAHYDROBENZO[B]THIOPHENE
نویسندگان
چکیده
منابع مشابه
Synthesis of fully substituted pyrimidines.
A novel approach to the synthesis of fully substituted pyrimidine derivatives armed with an oxy-functionalized acetate chain at the ring is described. The manifold uses amidines as the nitrogen source and activated skipped diynes as the electrophilic reactive partners in a coupled domino strategy. In the first domino reaction, two consecutive aza-Michael additions assemble the six-membered ring...
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ژورنال
عنوان ژورنال: Sinai Journal of Applied Sciences
سال: 2014
ISSN: 2682-3527
DOI: 10.21608/sinjas.2014.78455